The first description of Peyer's patches

PEYER, Johann Conrad.

Exercitatio anatomico-medica de glandulis intestinorum, earumque usu & affectionibus : cui subjungitur Anatome ventriculi gallinacei.

Schaffhausen: Onophrius a Waldkirch, 1677.

1st Edition. Soft cover. Very Good. Item #002044

8vo (150x94 mm), [28], 136, [6] pp. Separate half-title for the second text, 3 folding engraved plates, 3 leaves of plate explanations (possible cut and separated from one leaf) bound next to plates within text, title-page somewhat creased and with small tear to top margin not affecting text. Only little browned, otherwise clean and unmarked. Without cover (paper strip to spine). Good copy of an exceedingly rare work. ----

ADB XXV, 568; Garrison-Morton 1100; Waller 7359; Hirsch-Hubotter IV, 550 - FIRST EDITION. During the period when Peyer and his associates were conducting their research in Schaffhausen, the chemical processes governing digestion were unknown. In the present book, Peyer described what has come to be called "Peyer's patches," the lymphoid follicles in the small intestine that play a role in typhoid fever. Extremely rare: 9 copies located in OCLC. One copy with the same number of plates sold at Sotheby's in 2001 (Friedman Medical Library sale) for $13,200.
Erstes und wohl folgenreichstes Werk des Schweizer Mediziners Peyer (1653-1712), in der er die 'Noduli lymphatici aggregatii' des menschlichen Dünndarmes beschrieb, die er irrtümlich fur Drüsen hielt. Dieser Irrtum hielt sich bis in die Mitte des 19. Jahrhunderts, als Brucke den lymphatischen Charakter der vermeintlichen Drüsen erkannte. Obwohl schon 1645 Marco Aurelio Severino diese Strukturen beschrieben hatte, sind sie bis heute in der Medizin als "Peyersche Platten" bekannt.

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