Venice: Giovanni Antonio Pinelli, 1721.
1st Edition. Hardcover. 4to - over 9¾ - 12" tall. Very Good. Item #003224
De separatione fluidorum in corpore animali dissertatio physico-mechanico-medica. Venice: Giovanni Antonio Pinelli, 1721. , 362,  pp. Including half title, engraved frontispiece, title with engraved vignette, engraved headpieces, woodcut initials and tailpieces, errata leaf, one folding engraved plate. Handwritten index bound after second work. Signatures: [pi]4, A-Y8, z6. Text and plates crisp and clean, small waterstain to top margin of a few pages, finger soiling to p.137, few ink marginalia in contemporary hand, errata corrected in text. Inscribed on title-page "Bouillet - dono authoris." [Bound with:] BERNOULLI, Johannes. De motu musculorum, de effervescentia & fermentione dissertationes physico-mechanica... accedunt Petri Antonii Michelotti. Venice, 1721. , 123 (1] pp., half-title, title with engraved vignette, engraved headpieces, woodcut initials and tailpieces, 1 folding plate, errata on H6v. Signatures: [pi]4, *8, A-G8 H6. Text and plate crisp and clean. Inscribed on title-page: Bouillet - dono editoris." [Bound with:] SCHREIBER, Johann Friedrich. Observationes et cogitata de Pestilentia quae annis MDCCXXXVIII et MDCCXXXIX in Ucrainia grassata est. St-Petersburg: Typis Academiae Scientiarum, 1740. 45,  pp. Signatures: A-F4 [-F4], without final blank F4. 3 works and 5 short dissertations bound in one volume. 4to (270 x 195 mm). Contemporary vellum, spine with gilt-lettered morocco label, red-dyed edges (upper hinge split towards foot of spine, upper board with approx. 3 cm portion of vellum lost at foot, boards somewhat bowed, extremities and corners worn). Provenance: Bouillet, first two works presented by Michelotti according to inscriptions on titles. A very clean and crisp copy internally with wide margins. ----
I + II. WELLCOME, IV-131; BLAKE P.44 ET 304; OSLER, 2024 ET 3405. Riccardi II, 158. FIRST EDITION of Michelotti's treatise on the separation of fluids in animal bodies in which he deals with the function of the glandular organs. For iatro-mechanics, secretion is an essentially mechanical phenomenon, consisting in the selective separation of specific particles of fluid circulating in the vessels: they profess that blood already contains all the constituents and components of the various secretions, which can be found in blood plasma filtrates. Michelotti's teacher at Padua University Jacob Hermann, a disciple of Jacques Bernoulli, introduced him to differential and integral calculus and to two fundamental texts for the new iatro-mechanical doctrine, the Treaties De motu musculorum (1694) and From effervescentia and fermentation (1690) by Johann Bernoulli. In addition, Hermann revealed to him some original demonstrations that Michelotti later attributed in his essay De separatione fluidorum. By Hermann's means Michelotti was able to establish epistolary ties with Johann Bernoulli in 1714, and with Leibniz the following year. His correspondence with Bernoulli continued until the end of 1725 and was valuable to him, not only for the development of the De separatione fluidorum, but also for the compilation of his Animadversiones which he annexed to the second edition (Venice, 1721) of the two treatises of Bernoulli. On pp. 347-51 is a letter by Georg Wilhelm Leibniz that makes reference to the work of the Scottish physician Archibald Pitcairn, who had adopted the 'hydraulic' theory of medicine. In September 1715 Leibniz exchanged letters with the Venetian mathematician and pysician Pietro Angelo Michelotti on the subject of the separation of fluids. Leibniz's reply to Michelotti is entitled De secretione animali.
III. NLM/Blake 409. RARE FIRST EDITION of Schreiber's observations of the plague epidemic in St. Petersburg, 1737-39. Dissertations: BARON, Theodoro. Uni et trino, virgini deiparae. An humor perspiratorius sit excrementitius? Drop title. Typis Quillau, 1742, 4 pp. LALOUETTE, Petro. An nutrimentum tandem detrimenti corporis causa? Typis Quillau, 1743, 4 pp. DE MAGNY, Guil.
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