London: H. K. Lewis & Co., 1929.
1st Edition. Hardcover. 8vo - over 7¾ - 9¾" tall. Near Fine. Item #003267
4to (241 x 175 mm). Entire volume: vii , 407  pp., including half-title. Bound in 20th-century three-quarter calf over marbled boards, spine with 5 raised bands gilt decorated and ruled in compartments and with two gilt-lettered morocco labels in compartments, red-sprinkled edges, housed in a custom-made slip-case. Very little age-toned internally, half title reattached, a few upper corner tips torn away, short tears to upper margin of pp. /110 and lower margin of pp. 111/112; short tear to upper margin of pp. 113/114, entering the text (with an old tissue repair), tear to lower margin of plate facing p.194 (not affecting image), final leaf repaired in upper gutter. Provenance: Children's Hospital / Research Foundation Library (blue ink stamp to title-page), Library of the Children's Hospital Research Foundation Cincinnati, Ohio (embossed stamp on title-page, with the last line erased, ink accession number on verso of title-page); black ink stamp of "The Children's Hospital," mostly in the upper margin on pages 51, 151, 201, 251, 301, and 351, a few times with offsetting onto the facing page; pencil note at foot of p. . A fine, handsomely bound copy. ----
Printing and the Mind of Man / PMM 420a; Norman 798 (journal extract); DSB V, p.30; Garrison-M. 1933; Grolier Medicine 96; Heirs of Hippocrates 2320. FIRST ANNOUNCEMENT OF THE DISCOVERY OF PENICILLIN. This first printing of Fleming's announcement of the antibacterial properties of penicillin marking the dawn of the age of antibiotics. Fleming, however, was unable to stabilise the drug, but when, in 1940, Ernest Chain and Howard Florey succeeded in doing so, the full benefit of the drug was appreciated. Fleming, Chain and Florey shared the Nobel Prize for medicine in 1945. An offprint of the original article was published in 150 copies; but after Chain and Florey's later work, Fleming was so inundated with requests for copies of his original article that in 1944 he had privately printed a second edition of about 250 copies. The original offprint is rarely seen at auction, one copy sold for $126,750 in 2001 at Sotheby's. - Visit our website to see more images!
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