Milestones of Science Books

NISSL, Franz.

Sammelband with a collection of 11 bound offprints, 1892-1897.

Berlin / Leipzig: Georg Reimer / Veit & Co., 1892.

1st Edition. Hardcover. 8vo - over 7¾ - 9¾" tall. Very Good. Item #003505

Content:
1. Die Beziehungen der Nervenzellsubstanzen zu den thätigen, ruhenden and ermüdeten Zellzuständen. Offprint from: Allgemeine Zeitschrift fur Psychiatrie, 52 (1896), 8 pp. Berlin: Georg Reimer, 1896.
2. Mittheilungen zur Anatomie der Nervenzell. Offprint from: Allgemeine Zeitschrift fur Psychiatrie, 50 (1894), 8 pp. Berlin: Georg Reimer, 1894. Lacking pp. 5-6.
3. Der gegenwärtige Stand der Nervenzellenanatomie. Offprint from: Allgemeine Zeitschrift fur Psychiatrie, 51 (1895), 6 pp. Berlin: Georg Reimer, 1895.
4. Ueber experimentell erzeugte Veränderungen an den Vorderhornzellen des Rückenmarks bei Kanninchen mit Demonstration mikroskopischer Präparate. Offprint from: Allgemeine Zeitschrift fur Psychiatrie, 48 (1892), 8 pp. Berlin: Georg Reimer, 1892.
5. Die Hypothese der specifischen Nervenzellenfunction. Offprint from: Allgemeine Zeitschrift fur Psychiatrie, 54 (1897), 107 [1] pp. and 4 collotype plates of micro-photographs Berlin: Georg Reimer, 1897.
6. Mitteilungen zur pathologischen Anatomie der Dementia paralytica. Offprint from: Archiv für Psychiatrie, 28 (1896), 5 [1] pp.
7. Kritische Fragen der Nervenzellen-Anatomie. Offrint from: Neurologisches Zentralblatt, no. 3-4 (1896), 13 [1] pp. Leipzig: Veit & Co., 1896.
8. Über die sogenannten Granula der Nervenzellen. Offprint from: Neurologisches Zentralblatt, nos. 19, 21, 22 (1894), 23 [1] pp., text illustrations. Leipzig: Veit & Co., 1894.
9. Über die Nomenklatur in der Nervenzellenanatomie. Offprint from: Neurologisches Zentralblatt, nos. 2-3 (1895), 16 pp. Leipzig: Veit & Co., 1895.
10. Ueber Rosin's neue Färbemethode des gesammten Nervensystems und dessen Bemerkungen über Ganglienzellen. Offprint from: Neurologisches Zentralblatt, nos. 3-4 (1894), 13 [1] pp. Leipzig: Veit & Co., 1894.
11. Der gegenwärtige Stand der Nervenzellen-Anatomie und -Pathologie. Nach einem auf der 26. Versammlung des Vereins südwestdeutscher Irrenärzte gehaltenen Vortrags. Offprint from: Zentralblatt für Nervenheilkunde und Psychiatrie, 18 (1895), 22 pp.
Contemporary plum cloth and marbled boards, spine with gilt lettering (rubbing of extremities, spine sunned). All offprints bound without any printed wrappers. Handwritten content list at end. The text generally somewhat browned and dust-soiled at outer margins. Provenance: Lawrence S. Kubie; James Tait Goodrich (bookplates to front-pastedown); H. Houston Merritt (stamp to front pastedown). ----

FIRST EDITIONS. Franz Nissl (1860-1919) is best known "for the discovery of a granular basophilic substance, now called Nissl's bodies, that is found in the nerve cell body and the dendrites. In connection with this discovery he classified changes in the distribution and number of these granules following disease or the severing of the axon; coined the term nervöses grau, or gray nerve network, a misleading concept of a diffuse interconnection of all nerve processes; and, both alone and with Alois Alzheimer, made a detailed study of dementia paralytica, paying special attention to the behavior of microglia (rod cells). [. . .] The present stage of development of neurohistological techniques, inculding electron microscopy, makes possible an appraisal of Nissl's real scientific achievements. The granular basophilic Nissl's substance is an important ultrastructure of nerve cells, composed of ribosomes and the membranes of the endoplasmic reticulum. The Nissl bodies, in reacting to injury and toxins, mirror the life cycle of a neuron very closely, and the importance Nissl attached to them was fully justified. [. . .] Nissl's arguments against the neuron doctrine, which is based on areas of contact between neurons, survived in many quarters until recent times, when electron microscopy amply confirmed the early observations of his contemporary Ramón y Cajal, which Nissl's studies on dementia paralytica are still valid, his admirable attempt to discover a neuropathological cause for mental diseas.

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