London: Thomas Roycroft, 1660.
2nd Edition. Hardcover. 12mo - over 6¾ - 7¾" tall. Very Good. Item #003618
12mo (142 x 83 mm). , 376,  pp., including engraved frontispiece, typeset headpieces, errata leaf, two leaves of publisher's advers, leaf [pi]1 of frontispiece explanation bound at end, lacking the final two blank leaves R11-12. Signatures: [pi]2 A12 a6 B-R12 (-R11-12). Contemporary sheep, spine with 4 raised bands gilt in compartments, boards ruled in gilt, red sprinkled edges, original endpapers (head of spine slightly chipped, minor rubbing of leather). Text little age-toned, occasional minor spotting, creasing of 2 leaves, small light brown stain to upper blank margins of initial leaves. Provenance: illegible inscription on front pastedown. Very good copy. Collated and textually complete. ----
Wing W2833, NLM/Krivatsy 13021; this edition not in Wellcome. VERY RARE SECOND EDITION of Willis' first book, a collection of tracts on fermentation, fevers, and urine, originally published in London 1659. The first text "contains the earliest suggestion that fermentation is an intestinal or internal motion of particles" (Garrison-Morton); the second contains the first description of epidemic typhoid; and the third notes the sweet taste of urine in diabetes mellitus. - Visit our website to see more images!
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